参考文献
[1] 阴健. 中药现代研究与临床应用[M]. 北京: 学苑出版社, 1995:223.
[2] 刘晨江, 赵志鸿. 冬凌草的研究进展[J] . 中国药学杂志, 1998, 33( 10 ): 577.
[3] 张春玲,吴力军,田代真一,等.冬凌草甲素通过激活caspase 诱导HeLa 细胞凋亡[J].中国药理学通报,2003,19(5):521-525
[4] 张守伟,刘加军.复方冬凌草甲素对肺癌SPCA-1 细胞的端粒酶活性的影响[J].临床肺科杂志,2003,8(3):204-206
[5] Liu J J,Huang R W,Lin DJ, a1.Antiproliferation effects of oridonin on HPB—ALL cells and its mechanisms of ac.Tion[J].Am JHematol,2006.81(2):86—94.
[6] 朱国臣,肖大江,张亚男,等.冬凌草甲素对人鼻咽癌细胞CNE一2的抑制作用[J].时珍国医国药,2007,18(4):804.805.
[7] Liu J J,Huang R W,Lin DJ,et al,Anti-proliferative effects of oridonin on SPC—A-l cells and its mechanism of action[J.J Int Med Res,2004,32(6):617—625.
[8] Zhang J F,Liu J J,Liu P Q。et a1.Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL·7402 cells[J].Hepatol Res,2006,35(2):104-1lO.
[9] 薛宏伟,潘祥麟,杨尚军.冬凌草甲素诱导GBC.SD细胞凋亡及对bcl一2,p53,fas/apo一1和c—myc表达的影响[J].山东大学学报(医学版),2005,43(4):336-339.
[10] Ren K K,Wang H Z,Xie LP,el a1.The effects of oridoninon cell growth,cell cycle,cell migration and differentia·tion in melanoma cells[J].J Ethnopharmacol,2006,103(2):176—180.
[11] LiD,WuLJ,TashiroS,etal.Oridonininhibitedthetyrosinekinase activity and induced apoptosis in human epidermoid carcinoma A431 cells[J].Biol Pharm Bull,2007,30(2)254—260.
[12] 崔侨,田代真一,小野寺敏,等.冬凌草甲素通过诱导人宫颈癌HeLa细胞自噬下调凋亡的机制[J].药学学报,2007,42(1):35—39.
[13] Chen S,Gao J,Halicka H D,et a1.The cytostatic and cytotoxic effects of oridonin(Rubescenin),a diterpenoid from Rabdosia rubescens,on tumor cells of different lineage[J].Int J Oncol,2005,26(3):579—88.

