loadingProduct Data?Sheetβ-CyclodextrinCat. No.:CAS No.:分?式:分?量:作?靶点:作?通路:储存?式:HY-1072017585-39-9C??H??O??1134.98Influenza VirusAnti-infectionPowderIn solvent-20°C4°C-80°C-20°C3 years2 years6 months1 monthInhibitors?Agonists?Screening Libraries溶解性数据体外实验H2O : 38.75 mg/mL (34.14 mM; Need ultrasonic)Mass1 mg5 mg10 mgSolventConcentration制备储备液1 mM5 mM10 mM0.8811 mL0.1762 mL0.0881 mL4.4054 mL0.8811 mL0.4405 mL8.8107 mL1.7621 mL0.8811 mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；?旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存?式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个?内使?，-20°C 储存时，请在 1 个?内使?。BIOLOGICAL ACTIVITY?物活性β-Cyclodextrin 是?种环状多糖，由 α-D-吡喃型葡萄糖单元通过 α-(1,4) 糖苷键连接?成。β-Cyclodextrin 通常?于增强药物的溶解度。β-Cyclodextrin 具有抗流感病毒 H1N1 的活性。体外研究β-Cyclodextrin (Beta-cyclodextrin; β-CD) is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds, which presents a hydrophilic external surface and a hydrophobic internal cavity[1]. In the pharmaceutical industry, β-Cyclodextrin (β-CD) has often been used to enhance the solubility of drugs, such as indomethacin, naringin, celecoxib, and citric acid[2].REFERENCESPage 1 of 2 www.MedChemExpress.cn
[1].?Campos EVR, et al. Chitosan nanoparticles functionalized with β-cyclodextrin: a promising carrier for botanicalpesticides. Sci Rep. 2018 Feb 1;8(1):2067.[2].?Cui L, et al. Effect of β-cyclodextrin complexation on solubility and enzymatic conversion of naringin. Int J Mol Sci. 2012 Nov 5;13(11):14251-61.[3].?Goncharova EP, et al. A Novel Sulfonated Derivative of β-Cyclodextrin Effectively Inhibits Influenza A Virus Infection in vitro and in vivo. Acta Naturae. 2019 Jul-Sep;11(3):20-30.
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