2019.7 Vol. 38, No. 7Chinese J. Struct. Chem.1079-1085Synthesis, Crystal Structure and Antitumor Activity
of a Na(I) Coordination Polymer Based on 2-Propyl-4,5-imidazoledicarboxylic Acid and 1,10-Phenanthroline Ligands?TAI Xi-Shi②
ZHOU Xiao-Jing LIU Li-Li(College of Chemistry and Chemical Engineering,
Weifang University, Weifang 261061, China)ABSTRACT A new Na(I) coordination polymer, [Na2(Hpimdc)(H2pimdc)(phen)2]? (1), has
been synthesized by the reaction of NaOH with 2?propyl-4,5-imidazoledicarboxylic acid (H3pimdc)
and 1,10?phenanthroline (phen). The Na(I) coordination polymer 1 was characterized by
single-crystal X-ray diffraction analysis and elemental analysis. In 1, the bridged ligand Hspimdc
adopts two modes (singly deprotonated and doubly deprotonated) to coordinate with the Na(I) ion. The Na(l) ion is six-coordinated with three N atoms from a phen ligand and a H2pimdc ligand,
three O atoms from a Hpimdc ligand and two other different H2pimdc ligands. The Na(2) ion is
also six-coordinated with three N atoms from a phen ligand and a Hpimdc ligand, three O atoms
from a H2pimdc ligand and other two different Hpimdc ligands. Complex 1 exhibits a ID chain
structure built up by 2pimdc_ and //-Hpimdc2- ligands. The antitumor activities of complex 1
against human SGC7901, A549 and H08910 cells have been tested.Keywords: 2?propyl-4,5-imidazoledicarboxylic acid, Na(I) coordination polymer, synthesis,
crystal structure, antitumor activity; DOI: 10.14102/j.cnki.0254-5861.2011-22321 INTRODUCTIONDuring the past decades, metal coordination
tive properties such as luminescent sensor111 gas
adsorption1121, photoluminescence*1 catalytic114\\ antitumor activity\ ?⑻,and magnetism[l9]. Recently,
polymers constructed by organic bridging ligands have always been one of the hotspots in coordina-tion chemistry11'51, and many Na(I) coordination
some coordination polymers with bifunctional
ligand, 2?propyl-4,5-imidazoledicarboxylic acid, have been reported*20 -6On the other hand, only a few properties of coordination polymers with
2?propyl-4,5-imidazoledicarboxylic acid have been
polymer derivatives, such as tribenzoic acid⑹,
Schiff base⑺,diacetic acid凶,oxalate?, and dicya? namid』? complexes have been reported. Many
studied. Therefore, it is still meaningful to study the
structure and property of coordination polymers with 2-propyl-4,5-imidazoledicarboxylic acid. Our
coordination polymers constructed by carboxylate
ligands exhibited intriguing structures and distinc-
Received 26 October 2019; accepted 15 January 2019 (CCDC 1865711)① This work was supported by the National Natural Science Foundation of China (No. 21171132),the Project of Shandong Province Higher Educational Science and Technology Program (J14LC01) and Science Foundation of Weifang② Corresponding author. Tai Xi-Shi, born in 1971, professor, majoring in coordination chemistry. E-mail: taixishi@lzu.edu.cn or taixs@wfu.edu.cn
Tai Xi-Shi and Zhou Xiao-Jing contribute equally to this study