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实用癌症杂志2019年5月第34卷第5期 ThePracticalJournalofCancer?May2019?Vol34?No.5
甲状腺癌手术中甲状旁腺损伤的发生情况以及
相关危险因素分析
缪英杰 吴宝潮 夏 飞
【摘要】 目的 分析甲状腺癌手术中甲状旁腺损伤的发生情况?并对相关危险因素进行分析?方法 选取确诊并接受手术治疗的甲状腺癌患者75例纳入研究?收集患者基本信息?并对潜在影响手术效果的各种因素进行调查?术后统计甲状旁腺损伤的发生率以及潜在影响因素作用情况?结果 研究中纳入男性患者10例?女性患者65例?平均年龄5.33%?性别年龄分布以及甲状腺癌的AJCC分期两性间差别未见统计学意义?P>0.05?单侧与双侧肿瘤的分布比例分别为78.67%和21.33%?患者术中接受了单侧淋巴结清扫术者占50.67%?男性与女性之间的分布差异也均未见统计学意义?甲状旁腺损伤的发生率为12.00%?其中男性为20.00%?女性为10.77%?两性之间差别未见统计学意义?P>0.05?其中年龄≥45岁者的甲状旁腺损伤发生率为10.67%?高于年龄<45岁者水平(1.33%)?男性内部也见年龄≥45岁者更高?且差别均有统计学意义?均有P<0.05?损伤原因来自于钳夹挫伤、血供障碍以及误切等?借助回归模型对潜在影响甲状旁腺损伤的因素进行多因素分析?结果提示?男性、年龄≥45岁、AJCC分期高以及双侧肿瘤患者发生甲状旁腺损伤的风险更高?OR值分别为2.205、3.253、2.333以及3.159?结论 甲状腺癌手术中甲状旁腺损伤的发生率在9.77%?其中男性患者、年龄≥45岁、AJCC分期高以及双侧肿瘤患者发生甲状旁腺损伤的风险更高? 【关键词】 甲状腺癌?手术?甲状旁腺损伤?危险因素 DOI:10.3969/j.issn.1001 ̄5930.2019.05.034
中图分类号:R736.1 文献标识码:A 文章编号:1001 ̄5930(2019)05 ̄0812 ̄03
(44.09±4.52)岁?年龄≥45岁患者比例为62.67%?AJCC分期Ⅰ~Ⅳa期患者比例分别为73.33%、12.00%、9.33%和
AStudyTowardstheOccurrenceofParathyroidLesionsandRelatedRiskFactorsinThyroidCancerSurgery
MIUYingjie?WUBaochao?XIAFei. TonglingPeople'sHospital?Tongling?244000
tors.Methods Atotalof75patientswiththyroidcancerdiagnosedandundergoingsurgicaltreatmentwereincludedinthestud ̄y.Collectbasicinformationofthepatientsandinvestigatefactorsthatmayaffectthesurgicaloutcome.Theincidenceofparathy ̄roidinjuryandtheeffectofpotentialinfluencingfactorswerecalculatedaftersurgery.Results Thestudyincluded10malepa ̄62.67%?theproportionofpatientswithAJCCstagingI ̄IVawas73.33%?12.00%?9.33%?and5.33%?respectively.?distribu ̄tientsand65femalepatients?theaverageagewas(44.09±4.52)yearsold?theproportionofpatientsaged≥45yearswastionandthyroidcancerAJCCstagingshowednostatisticalsignificancebetweenthegenders?P>0.05?unilateralandbilateraltumorswere78.67%and21.33%?Inpatientsundergoingunilaterallymphadenectomy?50.67%wereperformed.Differencesin 【Abstract】 Objective Toanalyzetheincidenceofparathyroidinjuryinthyroidcancersurgeryandtherelatedriskfac ̄
20.00%inmalesand10.77%infemales.Therewasnostatisticallydifferencebetweengenders?P>0.05?amongfemales?thein ̄
distributionbetweenmenandwomenwerealsowithoutstatisticallysignificance.Theincidenceofparathyroidinjurywas12.00%?detectedamongmales?allP<0.05.AmultivariateanalysisoffactorsshowedthatpotentialfactorsthataffectedparathyroidglandwithanORof2.205?3.253?2.333?and3.159.Conclusion Theincidenceofparathyroidinjuryinthyroidcancersurgeryis 【Keywords】 Thyroidcancer?Surgery?Parathyroidinjury?Riskfactors
(ThePracticalJournalofCancer?2019?34:812~814)
cidenceofparathyroidinjurywhich≥45yearsoldwas10.67%?higherthantheones<45yearsold(1.33%)?similartrendwas
injuryincludedmalegender?age≥45years?higherAJCCstaging?andbilateraltumorshadahigherriskofparathyroidinjury?9.77%.Malepatients?age≥45years?highAJCCstage?andbilateraltumorpatientshaveahigherriskofparathyroidinjury.
作者单位:244000安徽省铜陵市人民医院
甲状腺癌属于1种实体恶性肿瘤?严重威胁人群健康[1 ̄2]?腺体全切手术存在1个重要问题就是容易