loading新生儿小时经皮胆红素百分位曲线图预测高胆红素血症价
值的多中心临床研究
新生儿高胆红素血症临床研究协作组
【期刊名称】《中华儿科杂志》 【年(卷),期】2015(053)011
【摘要】Objective To assess the predictive value of hour-specific transcutaneous bilirubin (TcB) nomogram for subsequent neonatal hyperbilirubinemia.Method Thirteen tertiary class-A hospitals (including two hospitals respectively in the northeastern, northern, eastern, south, northwest, southwestern regions of China, and one in central region) participated in this multicenter study between January 1 and December 31, 2013.All TcB measurements were obtained from healthy term and near-term newborns (gestational age ≥35 weeks, birth weight ≥ 2 000 g) by the JM-103 bilirubinometer between 0 and 168 postnatal hours.Developed an hour-specific TcB bilirubin nomogram with these data.Newborns were divided into 4 groups based on the predischarge bilirubin \ P40-P75 , ＞ P75-P95 , and ＞ P95 as low, low-intermediate, high-intermediate and high risk zones on the hour-specific
bilirubin
nomogram)
to
predict
subsequent
hyperbilirubinemia.Selected bilirubin measurements of three time quantums (25-48 h,49-72 h, 73-96 h) as a predictor for the respective danger zone, and adopted ROC curve to assess the predictive ability of